Research Directions

The Chen Lab at Peking University combines bioengineering, molecular biology, cell biology, fluorescence imaging, and nanotechnology to create novel nucleic acid-based methods for the detection and/or treatment of human diseases such as cancer and infectious diseases. Specific research interests include (i) Developing highly biostable and sensitive nucleic-acid nanodevices for intracellular analysis of RNA and chromatin dynamics that are key regulators of cellular physiology and pathogenesis; (ii) Constructing self-assembled RNA nanostructure-based therapeutics; (iii) Demystifying the role of viral and host cellular RNAs in retroviral assembly using advanced imaging techniques. Research in the Chen lab is currently supported by the National Key R&D Program of China and the National Natural Science Foundation of China.

The Chen Lab at Peking University combines bioengineering, molecular biology, cell biology, fluorescence imaging, and nanotechnology to create novel nucleic acid-based methods for the detection and/or treatment of human diseases such as cancer and infectious diseases. Specific research interests include (i) Developing highly biostable and sensitive nucleic-acid nanodevices for intracellular analysis of RNA and chromatin dynamics that are key regulators of cellular physiology and pathogenesis; (ii) Constructing self-assembled RNA nanostructure-based therapeutics; (iii) Demystifying the role of viral and host cellular RNAs in retroviral assembly using advanced imaging techniques. Research in the Chen lab is currently supported by the National Key R&D Program of China and the National Natural Science Foundation of China.