Principle Investigator

Antony K. Chen, Ph.D., Associate Professor

Department of Biomedical Engineering, College of Future Technology, Peking University
Office address: Yingjie Overseas Exchange Center 338E
Lab address: Integrated Science Research Center 112
TEL: +86-10-62768343
Email: chenak@pku.edu.cn
现任中国生物物理学会单分子生物学分会委员、中国遗传学会三维基因组学专业委员会委员。获得2023年拜耳学者奖。

Research Interests

Nucleic acid nanotechnology, Single-molecule imaging, Biomolecular engineering, Virus-like particle-based RNA delivery/vaccine technologies

Education

  • 2004–2008 Ph.D.; University of Pennsylvania (in Biomedical Engineering)
  • 2000–2002 M.S.; University of California, San Diego (in Biomedical Engineering)
  • 1996–2000 B.S.; University of California, San Diego (in Biomedical Engineering)

Major Professional Experiences

  • 2021.01–Present Associate Professor, Department of Biomedical Engineering, College of Future Technology, Peking University
  • 2019.08–2020.12 Associate Professor, Department of Biomedical Engineering, College of Engineering, Peking University
  • 2013.04–2019.07 Assistant Professor, Department of Biomedical Engineering, College of Engineering, Peking University
  • 2010–2013 Postdoc; National Institutes of Health; Jennifer Lippincott-Schwartz’s lab
  • 2010–2012 Postdoc; National Institute of Standards and Technology; Anne Plant’s lab
  • 2009–2010 Postdoc; University of Pennsylvania; Andrew Tsourkas’ lab

Funded Projects

  • 2024.01–2028.12 大体积样本与深层组织超高分辨率构象检测与全景成像装置研制(科技部国家重点研发计划课题) 课题骨干
  • 2022.01–2026.06 干细胞命运决定过程中胞核无膜颗粒小体的结构、定位、组成成分及其动态变化研究(科技部国家重点研发计划课题) 课题负责人
  • 2022.01–2025.12 活细胞中线粒体RNA实时可视化技术平台的建立和应用研究(国家自然科学基金面上项目) 课题负责人
  • 2017.01–2021.12 活细胞单分子成像内源RNA技术(国家自然科学基金面上项目) 课题负责人
  • 2016.07–2021.07 活细胞中蛋白质机器构象改变实时观测技术(科技部国家重点研发计划课题) 课题负责人
  • 2016.07–2021.07 非编码 RNA 介导的染色质高级结构动态变化对神经细胞谱系命运决定的调控功能及分子机制(外胚层)(科技部国家重点研发计划课题) 课题骨干
  • 2016.01–2018.12 引入Pentabase的分子信标再活细胞中的功能性研究与应用(北京市自然科学基金面上项目) 课题负责人
  • 2014.01–2017.12 新型分子信标研究及其在活细胞内HIV-1病毒RNA成像的应用(国家自然科学基金面上项目) 课题负责人